If you've heard anything about salvia, it probably had something to do with the 2010 video of Miley Cyrus allegedly using the drug. In many places, salvia use is completely unregulated, which might make it particularly tempting for people seeking a trip with fewer legal repercussions. The drug isn't as popular as you might think, however, because the effects it has are fairly unappealing.
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Even people who enjoy a good trip don't generally recommend salvia. The drug, actually an herb that's part of the mint family, produces effects unlike any other. Again, this is not as much of a positive as you might think. Salvia use results in a short, intense trip, which can include synesthesia (the crossing of different senses) and tactile hallucinations, such as the feeling of having bugs on your skin. It can also lead to altered perceptions of self and external reality, which may results in decreased control over interactions with one's environment.
Aside from the fact it sounds downright unpleasant, salvia use concerns some people because it seems to affect the brain in a unique way. There isn't a lot of research on this but what we do know is that, rather than binding to serotonin receptors (like most psychedelics), it binds to a dopamine-reducing opioid receptor.
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Read more about Salvia:
National Institute on Drug Abuse: Salvia
Why Is Salvia So Uniquely Terrifying?