First off, Kalamazoo isn't that exotic at all, unless you consider a small Midwestern city exotic. Kalamazoo - or "K-Zoo" as I've heard colloquially - is in the state of Michigan, about 140 miles directly west of Detroit along interstate I-94, almost the midway point between Detroit and Chicago. With a population of around 74,000, it is a small and humble city and college town - home of Kalamazoo College and Western Michigan University - with many characteristics and events to make it your ordinary all-American city. There are a few museums and an arts institute, plus food festivals, beer and wine tours, and a county fair. Kalamazoo's funny name comes from an old Native American word, which is also the namesake of Kalamazoo County and the Kalamazoo River.
Timbuktu is actually a bit more remote, although perhaps not the pinnacle of the excitement in terms of high adventure travel. It too is a small city typical for its region - on the southern fringe of the Sahara Desert in the western African country of Mali - where day to day life can seem rather ordinary; adults work to make a living while kids play soccer in its sandy streets and alleyways. There are several mud-built houses, stores, mosques, and tour offices for those wanting to go out into the desert, but otherwise, it's a pretty sleepy and anti-climactic town.