"What we are asking and looking for is ... a very few individuals who are actually walking around with the risk that normally would cause a disease, but something hidden in them is actually protective and keeping them from exhibiting those symptoms."
The research is part of a pilot study for what's been dubbed "The Resilience Project".
Friend and his team have now launched a follow-up project in which participants will submit their genetic data with the understanding they will be recontacted.
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Bob Williamson from the University of Melbourne, the former director of the Murdoch Children's Research Institute, is pleased researchers are focusing on the healthy, not just the sick.
"We spend all of our time looking at people who are sick and don't take into account that many people are very healthy indeed," he said.
"And this is sometimes in spite of the fact that they have a genetic mutation which in many people will cause the disease."
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Williamson said the work promised to create an extraordinary data bank of material for ongoing medical research.
"Cystic fibrosis is a disease that we assumed would be caused by a mutation and there was just no way around it," he said. "And yet they found people who had the mutations that cause cystic fibrosis, and because of other genes, because of other mutations, they did not develop the disease.
"Now this is really exciting because of the perspective it puts on human genetics."
Williamson said the information could be used to design new drugs to treat people who do develop diseases like cystic fibrosis.
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"The most exciting thing for me about this is that so far it's been used to look at diseases like cystic fibrosis where a single gene, a single mutation is causing the condition," he said. "But what about cancer, what about heart disease, what about type 2 diabetes?
"These are complex conditions with several genes, and the environment is involved, and yet most people ... who are overweight don't develop type 2 diabetes."
The study was published Tuesday in the journal Nature Biotechnology.
This originally appeared on ABC Online.