"I just want to say for Oleg and me, we are really proud of being part of such a team and flying with Peggy. Peggy is a legend, but she is also absolutely unbelievable to work with or just hang around with and live with in space," said Pesquet.
"We are, of course, going to miss Oleg and Thomas," said Whitson. "They're exceptional astronauts in every sense of the word. But mostly, we are going to miss their sense of humor and camaraderie."
Novitskiy and Pesquet served on the space station's 50th and 51st expedition crews. Their undocking aboard Soyuz MS-03 from the orbiting complex's Rassvet module at 6:47 a.m. EDT (1047 GMT) marked the beginning of Expedition 52 with Yurchikhin in command.
Three more crewmates, Sergei Ryazansky of Roscosmos, Randy Bresnik of NASA and Paolo Nespoli of ESA, are set to launch on Soyuz MS-05 on July 28.
During Novitskiy and Pesquet's time in space, they helped to conduct a multitude of science experiments, including a payload of European investigations flown to the station as part of Pesquet's "Proxima" mission. The two also saw the departure of the Russian Progress MS-03 cargo craft and arrival of Progress MS-05, and they helped receive and unpack the S.S. John Glenn, a U.S. commercial freighter launched by Orbital ATK for NASA.
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Pesquet also went out on two spacewalks with Expedition 50 commander Shane Kimbrough to connect a new set of batteries on the exterior of the station and to prepare one of the outpost's ports for the future installation of a docking adapter to support U.S. commercial crew spacecraft.
In total, Pesquet logged 12 hours and 32 minutes on the extravehicular activities (EVA), the first two of his career.
"It's been a fantastic adventure and amazing ride," wrote Pesquet on Twitter on Friday of his time in orbit, which was also his first time flying in space. Pesquet, 39, is the tenth French astronaut and the last of the 2009 ESA astronauts, nicknamed the "Shenanigans," to fly in space.
Novitskiy, 45, has now logged more than 340 days in orbit on his two missions, including a 144-day stay on the space station during Expeditions 33/34 in 2013.
Pesquet's and Novitskiy's return to Earth marked the first two-man Soyuz landing since March 2010, when cosmonaut Maxim Surayev and astronaut Jeff Williams completed Expedition 21 on board Soyuz TMA-16.
Whitson's empty seat aboard Soyuz MS-03 was filled with a cargo carrier for the return to Earth.
Now safely home from space, Novitskiy and Pesquet will be flown to the Kazakh town of Karaganda for a traditional welcome ceremony and then they will split ways, Novitskiy flying to Star City in Russia and Pesquet heading for the European Astronaut Center in Cologne, Germany.
Soyuz MS-03 was the 49th Soyuz to fly to the International Space Station. It traveled 82.9 million miles (133.4 million kilometers) over the course of 3,136 orbits of Earth.
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