Sunday's Falcon 9 launch of a Dragon capsule to the space station went off, but not without a hitch. During the rocket's ascent, one of its nine Merlin engines shut down prematurely one minute and 19 seconds after launch.
In the ensuing press release, SpaceX pointed out that engine malfunctions are neither abnormal nor crippling, and pointed out that the Saturn V experienced two engine malfunctions. It did, and neither were fatal to the mission.
More than one Saturn V had problems during launch. The Saturn V that took Apollo 12 to the moon, for example, was struck by lightning twice in the first minute of its flight. And two rockets did experience engine failures, Apollo 6 and Apollo 13. In both cases it was second stage engines that failed, and in the case of Apollo 13, it didn't affect the spacecraft's orbital insertion at all.
Apollo 6 launched on April 4, 1968. It was an unmanned mission designed to demonstrate compatibility between the Saturn V rocket and the Apollo Command and Service Module (CSM). The mission would also give ground crews a chance to practice tracking and controlling a spacecraft in orbit.