Costing between $20 to $30, the kit will be on sale at some 7,500 branches of Walgreens from the weekend, except those in New York state, due to local laws.
After sending off the swab, the customer has to log onto the Pathway Genomics site and create a personal account to order the tests they are interested in, out of three proposed sets costing up to $249.
By analyzing the client's DNA, the company can test for markers which could indicate whether the person is at risk for about 70 diseases, including breast or prostate cancer, heart disease, diabetes or rheumatoid arthritis.
They can also test for responses to drugs such as anti-cholesterol medication, the anti-coagulant warfarin or tamoxifen used to battle breast cancer.
Couples can also spend $179 if they wish to know whether they risk passing on hereditary diseases such as cystic fibrosis to their future children.
"Everyone has the right to know the secrets hidden within their own DNA," the company says on its website. "With personal DNA testing, you can take preventative steps to improve your future, and even extend your life."