Between 1990 and 2005, lions killed 563 people in Tanzania, Africa, reported a paper in Nature. One of those lions stalked Rufiji, Tanzania, from 2002 to 2004, killing an estimated 50 people. The lion received the moniker Osama, after the infamous terrorist. Osama stalked the region until he was shot in 2004.
Normally, old or sick males that have been cast out of their prides make a habit of hunting humans. However Osama was only 3 years old and in good health. Female lions actually kill more humans in isolated events, University of Minnesota lion expert Craig Packer told the Smithsonian, but males tend to become habitual man-eaters.