Hawking believes the answer to this big question lies in M-theory, an extension to superstring theory, and that the Large Hadron Collider (LHC), located on the Franco-Swiss border near Geneva, Switzerland, could start detecting hints of supersymmetric particles in the not-so-distant future.
Although much of the discussion was based around black holes, multiverses and the apparent incompatibilities of Einstein's general theory of relativity and quantum mechanics, he did have some time to comment on the recent discovery of the much-sought after Higgs boson.
"It looks like I've lost another bet," Hawking joked during his presentation to the capacity audience.
Hawking famously placed a $100 bet against fellow physicist Gordon Kane of Michigan University on the Higgs boson not being discovered. But shortly after CERN announced that the LHC had discovered a "Higgs-like particle" on July 4, 2012, he admitted the odds of him winning the bet had become very slim.
"This is an important result and should earn Peter Higgs the Nobel Prize," said Hawking in 2012. "But it is a pity in a way because the great advances in physics have come from experiments that gave results we didn't expect."