Three cases of Zika virus, Florida's first, were recorded in people who had recently traveled in Latin America, health authorities said Wednesday.
The first two cases were found in Miami-Dade County, in people who visited Colombia in December.
The third case, in Hillsborough County, involved a person who traveled to Venezuela last month, Florida Health Department spokeswoman Mara Gambineri said.
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"We encourage Florida residents and visitors to protect themselves from all mosquito-borne illnesses by draining standing water, covering their skin with repellent and clothing, covering windows with screens," Gambineri said.
No cases have yet been confirmed of infections contracted in the United States, though the virus has quickly spread across South America and the Caribbean in recent weeks.
The Zika virus, which is transmitted by mosquitoes, cannot spread between humans.
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But for pregnant women, the virus can be transmitted to the fetus, triggering brain damage like microcephaly in which the brain and skull are abnormally small.