The scientists are now using their findings "to design new studies that aim to understand how this variant influences metabolism and disease," study co-authorTeresa Tusie-Luna, principal investigator at the National University of Mexico's Biomedical Research Institute, said in a statement.
These insights could "illuminate new pathways to target with drugs and a deeper understanding of the disease," study co-author José Florez, from the Broad Institute and Harvard Medical School, said in a statement.
The researchers cautioned that Type 2 diabetes is a complex disease influenced by multiple genes and by environment and behavior. "Our finding is only one piece in a large and complex puzzle," Altshuler said. "Any clinical translation of this finding will take many years. It is still in the research phase, and any health benefits will take time."
The scientists detailed their findings online Dec. 25 in the journal Nature.
Original article on LiveScience.
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