Tragically, Bruno ran afoul of the Roman Catholic Church, which imprisoned and killed him. Bruno's story was told by Tyson through wonderful animated shorts that enhanced his awesome storytelling abilities.
From Bruno's realization about the true scale of the universe, the episode spiraled out to the Cosmic Calendar - first popularized by Sagan in the original "Cosmos" - where the entirety of the history of the universe is mapped onto our 365-day year. If the Big Bang occurred on Jan. 1, the whole of human history occurred in the final few seconds of Dec. 31.
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"Feeling a little small?" asks Tyson. That was the crux of this entire episode: the scale of the universe is unfathomable and our place in it is baffling, but Cosmos is here to help the audience join the dots and hopefully grasp the immensity of the questions science is asking.
Throughout the show we are treated to some of the best CGI television has to offer and, for the most part, the computer-generated renderings are scientifically sound (give or take a bit of latitude for dramatic license). Personally, I loved the beach scene where Tyson is describing how life from the oceans evolved to venture onto the land - seamlessly a CGI Tiktaalik, one of the first animals to venture out of the oceans, lumbered onto the beach and it took a moment for me to realize it wasn't real.